Lipoic Acid Benefits Alzheimer's Patients
Lipoic Acid Benefits Alzheimer's PatientsAccording to a study in the Archives of Gerontology and Geriatrics, alpha-lipoic acid may be an important neuroprotective nutrient in Alzheimers patients.
The researchers theorized that since oxidative stress and energy depletion characterize Alzheimers disease, antioxidants that can positively affect glucose metabolism such as alpha-lipoic acid should benefit anyone with this disease. To test their hypothesis, the scientists gave 600 mg lipoic acid daily to nine patients with Alzheimers or related dementias who were also receiving a standard drug treatment with acetylcholinesterase inhibitors. The open study, conducted over an average of 337±80 days, demonstrated that cognitive functions stabilized in the lipoic-acid group. The patients receiving lipoic acid achieved constant scores in two neuropsychological tests.
Despite the fact that this study was small and not randomized, the study authors wrote, this is the first indication that treatment with lipoic acid might be a successful neuroprotective therapy option for AD and related dementias.
Klaus Hagera, Andres Marahrensa, Marlene Kenkliesa, Peter Riedererb, Gerald Münchc. Alpha-lipoic acid as a new treatment option for Alzheimer type dementia. Arch Gerontol Geriatr. 2001 June; 32(3): 275 - 82.
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