L-theanine Must be Pure for Proper Absorption, Study FindsA new study finds that L-theanine must be administered in its pure form rather than as the mixture of D-theanine and L-theanine found in many nutritional supplements in order to be absorbed by the body.
Researchers from Iowa State University orally administered to rats pure L-theanine, pure D-theanine, and an ingredient commercially marketed as ?L-theanine? that actually was a racemic mixture (a 50:50 split between D- and L-theanine). They then measured blood concentrations, urinary excretion, and a marker of theanine metabolism in the blood.
The results show that the animals? bodies had a preference for pure L-theanine and that the pure form is better absorbed in the gut. The concentration of L-theanine seen in the blood was greater with the pure L-theanine than it was with the racemic mixture. There was also a trend toward greater urinary excretion of L-theanine when consumed as the racemic form.
The majority of clinical and animal studies determining the
bioavailability of L-theanine have used Suntheanine, a form of
For the benefits of L-theanine and technical information click here
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